Shinichi Oka Selected Research

Ritonavir (Norvir)

7/2018	Tenofovir disoproxil fumarate co-administered with lopinavir/ritonavir is strongly associated with tubular damage and chronic kidney disease.
1/2016	Nonnucleoside Reverse-transcriptase Inhibitor- vs Ritonavir-boosted Protease Inhibitor-based Regimens for Initial Treatment of HIV Infection: A Systematic Review and Metaanalysis of Randomized Trials.
12/2014	Single-nucleotide polymorphisms in the UDP-glucuronosyltransferase 1A-3' untranslated region are associated with atazanavir-induced nephrolithiasis in patients with HIV-1 infection: a pharmacogenetic study.
5/2014	Cumulative exposure to ritonavir-boosted atazanavir is associated with cholelithiasis in patients with HIV-1 infection.
4/2014	Skin rash induced by ritonavir-boosted darunavir is common, but generally tolerable in an observational setting.
10/2013	Urinary beta-2 microglobulin and alpha-1 microglobulin are useful screening markers for tenofovir-induced kidney tubulopathy in patients with HIV-1 infection: a diagnostic accuracy study.
1/2013	Ritonavir-boosted darunavir is rarely associated with nephrolithiasis compared with ritonavir-boosted atazanavir in HIV-infected patients.
1/2013	Abacavir/lamivudine versus tenofovir/emtricitabine with atazanavir/ritonavir for treatment-naive Japanese patients with HIV-1 infection: a randomized multicenter trial.
1/2013	Pharmacokinetics of rifabutin in Japanese HIV-infected patients with or without antiretroviral therapy.
1/2013	Is ritonavir-boosted atazanavir a risk for cholelithiasis compared to other protease inhibitors?

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Shinichi Oka Research Topics

Disease

66	Infections 01/2022 - 04/2002
31	Acquired Immunodeficiency Syndrome (AIDS) 09/2021 - 01/2002
21	HIV Infections (HIV Infection) 01/2022 - 01/2002
16	Disease Progression 11/2021 - 04/2002
10	Stroke (Strokes) 07/2022 - 11/2016
9	Body Weight (Weight, Body) 07/2019 - 08/2006
8	Hepatitis C 02/2020 - 04/2002
7	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 02/2022 - 08/2009
7	Stomach Neoplasms (Stomach Cancer) 02/2022 - 12/2017
6	Syphilis 01/2020 - 01/2015
6	Neoplasms (Cancer) 10/2019 - 02/2007
6	Lymphoma (Lymphomas) 02/2014 - 09/2003
5	Spinal Cord Injuries (Spinal Cord Injury) 07/2022 - 10/2016
5	Fibrosis (Cirrhosis) 01/2021 - 06/2011
5	Hepatitis B 12/2019 - 03/2013
5	Kaposi Sarcoma (Kaposi's Sarcoma) 01/2019 - 09/2006
5	Coinfection 11/2018 - 01/2013
5	Retinitis 02/2015 - 01/2002
5	Hypersensitivity (Allergy) 04/2014 - 01/2007
4	Lipodystrophy 01/2022 - 01/2002
4	Hemophilia A (Haemophilia) 01/2022 - 06/2011
4	Ischemia 01/2019 - 04/2013
4	Inflammation (Inflammations) 01/2019 - 01/2016
4	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2019 - 05/2008
4	Viremia 01/2018 - 02/2002
3	Ischemic Stroke 07/2022 - 10/2017
3	Opportunistic Infections (Opportunistic Infection) 02/2022 - 01/2002
3	Atrophy 01/2022 - 01/2002
3	Brain Ischemia (Cerebral Ischemia) 12/2021 - 11/2016
3	Papillomavirus Infections 01/2021 - 03/2014
3	Myocardial Infarction 09/2020 - 11/2010
3	Heart Failure 09/2020 - 11/2011
3	Pathologic Constriction (Stenosis) 10/2019 - 04/2002
3	Cerebral Infarction 02/2019 - 01/2018
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 02/2019 - 10/2017
3	Chronic Renal Insufficiency 07/2018 - 01/2013
3	Anemia 01/2017 - 07/2005
3	AIDS-Related Lymphoma (Lymphoma, AIDS Related) 08/2013 - 04/2006
3	Necrosis 01/2012 - 09/2006
3	Lactic Acidosis 05/2007 - 04/2002
3	Vaccinia 11/2005 - 06/2003
2	COVID-19 04/2022 - 10/2021
2	Bacteremia 03/2022 - 01/2002

Drug/Important Bio-Agent (IBA)

19	EpitopesIBA 12/2019 - 06/2003
18	Tenofovir (Viread)FDA Link 09/2021 - 01/2011
14	Pharmaceutical PreparationsIBA 12/2022 - 01/2003
14	HLA-B Antigens (HLA-B)IBA 11/2021 - 01/2005
12	Ritonavir (Norvir)FDA Link 07/2018 - 08/2002
11	VaccinesIBA 12/2019 - 06/2003
8	RNA (Ribonucleic Acid)IBA 01/2017 - 09/2003
7	Peptides (Polypeptides)IBA 01/2022 - 06/2003
7	Reverse Transcriptase InhibitorsIBA 09/2021 - 08/2003
7	Protease Inhibitors (Protease Inhibitor)IBA 09/2021 - 01/2013
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2002
7	HLA-A Antigens (HLA-A)IBA 01/2019 - 05/2005
6	Atazanavir Sulfate (Reyataz)FDA Link 09/2021 - 01/2013
6	Lopinavir FDA Link 09/2021 - 08/2002
6	Darunavir (Prezista)FDA Link 09/2021 - 03/2012
6	Antiviral Agents (Antivirals)IBA 02/2020 - 05/2007
5	HLA-C Antigens (HLA-C)IBA 01/2022 - 07/2015
5	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022 - 11/2005
5	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 12/2005
5	Emtricitabine (Emtriva)FDA Link 09/2021 - 01/2013
5	abacavir (Ziagen)FDA Link 09/2021 - 02/2008
5	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2017 - 01/2002
4	elvitegravirIBA 09/2021 - 06/2015
4	CreatinineIBA 01/2021 - 01/2011
4	Rilpivirine (TMC-278)IBA 01/2021 - 10/2016
4	Therapeutic UsesIBA 01/2021 - 11/2016
4	Sirtuin 1IBA 11/2014 - 11/2010
4	SteroidsIBA 01/2013 - 01/2006
3	Azithromycin (Zithromax)FDA LinkGeneric 10/2021 - 01/2019
3	NucleosidesIBA 09/2021 - 05/2007
3	tenofovir alafenamideIBA 09/2021 - 06/2015
3	HLA-B*52:01 antigenIBA 01/2021 - 01/2017
3	lamivudine drug combination abacavir FDA Link 01/2020 - 03/2012
3	ReaginsIBA 01/2020 - 07/2015
3	CobicistatIBA 07/2019 - 06/2015
3	Protein Isoforms (Isoforms)IBA 01/2019 - 01/2013
3	AIDS VaccinesIBA 01/2019 - 03/2009
3	Formaldehyde (Formol)FDA Link 06/2018 - 01/2017
3	ParaffinIBA 06/2018 - 01/2017
3	InterferonsIBA 01/2018 - 06/2011
3	Stavudine (Zerit)FDA LinkGeneric 12/2017 - 01/2014
3	HLA-B57 antigenIBA 01/2017 - 04/2009
3	Ribavirin (Virazole)FDA LinkGeneric 01/2017 - 04/2002
3	Illicit Drugs (Recreational Drugs)IBA 02/2014 - 01/2013
2	AnticoagulantsIBA 07/2022 - 02/2020
2	liposomal amphotericin B FDA Link 01/2022 - 01/2019
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2021 - 12/2012
2	Doxycycline (Periostat)FDA LinkGeneric 10/2021 - 01/2021

Therapy/Procedure

65	Therapeutics 07/2022 - 04/2002
20	Highly Active Antiretroviral Therapy (HAART) 09/2021 - 01/2002
18	Intravenous Infusions 07/2022 - 10/2016
11	Art Therapy 12/2020 - 01/2012
6	Drug Therapy (Chemotherapy) 12/2022 - 02/2014
5	Gastrectomy 02/2022 - 07/2017
3	Gastroenterostomy 02/2022 - 01/2018
3	Stents 10/2019 - 09/2005
3	Transplantation 06/2011 - 03/2011